BDBM50460717 CHEMBL4229266

SMILES CCN(CC)C(=O)c1ccc(Nc2nccc(NC(=O)Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1

InChI Key InChIKey=UXXAXUKFKIABIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460717   

TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology Co. Itd.

Curated by ChEMBL
LigandPNGBDBM50460717(CHEMBL4229266)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M mutant cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology Co. Itd.

Curated by ChEMBL
LigandPNGBDBM50460717(CHEMBL4229266)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild-type EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed