BDBM50461530 CHEMBL4227032

SMILES OC(=O)C[C@H](NC(=O)C1CCN(CC1)C(=O)c1ccc(Cl)s1)C(=O)COc1c(F)c(F)cc(F)c1F

InChI Key InChIKey=PJKBOZXYEDFYLA-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461530   

TargetCaspase-3(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461530(CHEMBL4227032)
Affinity DataIC50:  20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed