BDBM50462969 CHEMBL4242359

SMILES COc1ccc2C(=O)\C(Cc2c1)=C/c1ccccc1-c1ccc2ccccc2c1

InChI Key InChIKey=YPSKYNKEQAAUJV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50462969   

TargetAcetylcholinesterase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462969BDBM50462969(CHEMBL4242359)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462969BDBM50462969(CHEMBL4242359)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462969BDBM50462969(CHEMBL4242359)
Affinity DataIC50: 101nMAssay Description:Inhibition of human BACE-1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCholinesterase(Horse)
Mansoura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462969BDBM50462969(CHEMBL4242359)
Affinity DataIC50: 101nMAssay Description:Inhibition of horse serum BuChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Mansoura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462969BDBM50462969(CHEMBL4242359)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of horse serum BuChE using acetylthiocholine as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed