BDBM50462971 CHEMBL4244803

SMILES COc1ccc(cc1)-c1ccccc1\C=C1\Cc2cc(OC)ccc2C1=O

InChI Key InChIKey=XRCNYIUXDHNUNU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50462971   

TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462971BDBM50462971(CHEMBL4244803)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462971BDBM50462971(CHEMBL4244803)
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462971BDBM50462971(CHEMBL4244803)
Affinity DataIC50: 99nMAssay Description:Inhibition of BACE-1 (unknown origin) measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCholinesterase(Horse)
Mansoura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462971BDBM50462971(CHEMBL4244803)
Affinity DataIC50: 99nMAssay Description:Inhibition of horse serum BuChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Mansoura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462971BDBM50462971(CHEMBL4244803)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of horse serum BuChE using acetylthiocholine as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed