BDBM50463244 CHEMBL4251414

SMILES CCCc1nc2cc(cc(C)c2[nH]1)C(=O)N1CCC2(CN(C(=O)C2)c2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=KNMQLFMUYKASBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463244   

TargetAcetyl-CoA carboxylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463244(CHEMBL4251414)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human ACC1 (1 to 2383 residues) expressed in Baculovirus infected Sf9 insect cells using acetyl CoA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463244(CHEMBL4251414)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human ACC2 expressed in Baculovirus infected Sf9 insect cells using acetyl CoA as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed