BDBM50463627 CHEMBL4247926

SMILES CNc1ccc(Nc2ncnc3occ(C)c23)cc1

InChI Key InChIKey=GUDRBAIOGCBSOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463627   

TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463627(CHEMBL4247926)
Affinity DataIC50: 200nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463627(CHEMBL4247926)
Affinity DataIC50: 200nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463627(CHEMBL4247926)
Affinity DataIC50: 200nMAssay Description:Inhibition of PDGF-BB-induced PDGFRbeta activation in human SH-SY5Y cells pretreated for 60 mins followed by PDGF-BB addition and measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed