BDBM50463912 CHEMBL4242333

SMILES O=C(Nc1ccccc1)c1c2c(C(=O)c3ncccc3C2=O)n2ccccc12

InChI Key InChIKey=DQTGGEGJZDHXIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463912   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50463912(CHEMBL4242333)
Affinity DataIC50: 361nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in N'-formlylkynurenine formation using D-Tryptophan as substrate in presence of aspartate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50463912(CHEMBL4242333)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of recombinant TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-Tryptophan as substrate after 75 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed