BDBM50464097 CHEMBL4237868
SMILES Cc1nc(C)n(n1)-c1cccc(c1)[C@@H](CN1CC[C@@H](CCc2ccc3CCCNc3n2)C1)CC(O)=O
InChI Key InChIKey=JWYJAXVOVLDVAL-ZJSXRUAMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50464097
Affinity DataKi: 0.0631nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by Q-patch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human integrin alphaVbeta3 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human integrin alphaVbeta1 expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human integrin alphaVbeta8 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by Barracuda automated patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human integrin alphaVbeta5 expressed in human K562 cells assessed as reduction in cell adhesion to vitronectin after 30 mins b...More data for this Ligand-Target Pair