BDBM50464103 CHEMBL4245368

SMILES Cc1cn(C)c(n1)-c1cccc(c1)[C@@H](CN1CC[C@@H](CCc2ccc3CCCNc3n2)C1)CC(O)=O

InChI Key InChIKey=CJMISCRXEFTMEV-PXDATVDWSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50464103   

TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human integrin alphaVbeta1 expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50:  7.90nMAssay Description:Antagonist activity at human integrin alphaVbeta8 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by Barracuda automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at human integrin alphaVbeta3 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at human integrin alphaVbeta5 expressed in human K562 cells assessed as reduction in cell adhesion to vitronectin after 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by Q-patch assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed