BDBM50464413 CHEMBL4281712

SMILES COc1ccc2ccc3CCC(CNC(C)=O)c3c2n1

InChI Key InChIKey=VRXWYUUUGIBVNR-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50464413   

TargetMelatonin receptor type 1B(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50464413(CHEMBL4281712)
Affinity DataKi:  0.200nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMelatonin receptor type 1A(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50464413(CHEMBL4281712)
Affinity DataKi:  0.400nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50464413(CHEMBL4281712)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-mesulergine from human 5-HT2C receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMelatonin receptor type 1A(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50464413(CHEMBL4281712)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed