BDBM50465257 CHEMBL4280225::US11299480, Example 43

SMILES C[C@@H](N(C)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(C)c1

InChI Key InChIKey=XYINRANQEXOIEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465257   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM50465257(CHEMBL4280225 | US11299480, Example 43)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii

US Patent
LigandPNGBDBM50465257(CHEMBL4280225 | US11299480, Example 43)
Affinity DataIC50: 6.60E+3nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
US Patent