BDBM50465456 CHEMBL4283703
SMILES Clc1ccc2C3CNC4CCC34Oc2n1
InChI Key InChIKey=CRXFCGUGNWJSEY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50465456
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]epibatidine from alpha7 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting metho...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 750nMAssay Description:Agonist activity at rat alpha3beta4 nAChR by cell-based rubidium flux assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 1.90E+4nMAssay Description:Agonist activity at rat alpha3beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
Affinity DataEC50: 9.90E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 3.10nMAssay Description:Agonist activity at rat alpha4beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Agonist activity at human alpha4beta2 nAChR by cell-based rubidium flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+4nMAssay Description:Agonist activity at rat 5HT3A expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair