BDBM50465675 CHEMBL4282828

SMILES COc1ccccc1NC(=O)Nc1cc(ccc1O)S(N)(=O)=O

InChI Key InChIKey=TYTZFKRSGVNIDM-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465675   

TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human CA12 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
ArticlePubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  23nMAssay Description:Inhibition of human CA9 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
ArticlePubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  255nMAssay Description:Inhibition of human CA1 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
ArticlePubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  951nMAssay Description:Inhibition of human CA2 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
ArticlePubMed