BDBM50465711 CHEMBL1316881

SMILES CN(CC(=O)Nc1ccc(F)c(F)c1F)C(=O)c1ccc2OCCOc2c1

InChI Key InChIKey=XITZPIXICJOKTF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465711   

TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human LXRalpha-LBD (182 to 447 amino acids) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human LXRbeta-LBD (196 to 461 amino acids) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPhospholipid-transporting ATPase ABCA1(Homo sapiens)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of ABCA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  0nMAssay Description:Activation of SREBP1c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed