BDBM50465790 CHEMBL4284117

SMILES CC1(C)CC(CC(C)(C)O1)c1cc(-c2ccc(Cl)cc2)n(n1)-c1ccccn1

InChI Key InChIKey=OTJRAMSCZBZACF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465790   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50465790(CHEMBL4284117)
Affinity DataIC50:  12nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50465790(CHEMBL4284117)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed