BDBM50466303 CHEMBL4282932

SMILES [H][C@]12O[C@@]3(C)CC[C@@]4([H])[C@H](C)CC[C@@]([H])([C@@H](C)[C@@H](CC(=O)N5CCN(CC5)c5ccc(C(=O)NS(=O)(=O)c6ccc(NCC7CCOCC7)c(c6)[N+]([O-])=O)c(Oc6cnc7[nH]ccc7c6)c5)O1)[C@@]24O3

InChI Key InChIKey=UXROYCPTOCMXGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466303   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466303(CHEMBL4282932)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466303(CHEMBL4282932)
Affinity DataIC50: 270nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed