BDBM50466305 CHEMBL4278774

SMILES [H][C@@]12CC[C@@]3(C)OO[C@]11C(O[C@H](OC)[C@@](C)(CC(=O)N4CCN(CC4)c4ccc(C(=O)NS(=O)(=O)c5ccc(NCC6CCOCC6)c(c5)[N+]([O-])=O)c(Oc5cnc6[nH]ccc6c5)c4)[C@]1([H])CC[C@H]2C)O3

InChI Key InChIKey=FJJRERLCWDCKRW-UTCXOHKZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466305   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466305(CHEMBL4278774)
Affinity DataIC50:  35nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466305(CHEMBL4278774)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed