BDBM50466312 CHEMBL4279038

SMILES [H][C@]12O[C@@]3(C)CC[C@@]4([H])[C@H](C)CC[C@@]([H])(C(CN5CCN(CC5)c5ccc(C(=O)NS(=O)(=O)c6ccc(NCC7CCOCC7)c(c6)[N+]([O-])=O)c(Oc6cnc7[nH]ccc7c6)c5)=C(O1)C(F)(F)F)[C@@]24O3

InChI Key InChIKey=FSOKCGWDPWOLON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466312   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466312(CHEMBL4279038)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466312(CHEMBL4279038)
Affinity DataIC50: 970nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed