BDBM50466313 CHEMBL4288614

SMILES [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OCCN1CCN(CC1)c1ccc(C(=O)NS(=O)(=O)c3ccc(NCC5CCOCC5)c(c3)[N+]([O-])=O)c(Oc3cnc5[nH]ccc5c3)c1)[C@@H]2C)O4

InChI Key InChIKey=KRKJAXWNKBNZQP-SFTSYJTKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466313   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466313(CHEMBL4288614)
Affinity DataIC50:  5nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466313(CHEMBL4288614)
Affinity DataIC50:  279nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466313(CHEMBL4288614)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed