BDBM50467112 CHEMBL4287557

SMILES C[C@@H](OP(O)(O)=O)[C@@H]1NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[n+](CCCCCNC1=O)cn2CCCCCCCCc1ccccc1)NC(C)=O

InChI Key InChIKey=BXUVUZFLIDJEID-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467112   

TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 8nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 370nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed