BDBM50468248 CHEMBL4290869

SMILES CC(C)(O)CC(=O)NCCc1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c2c1

InChI Key InChIKey=PDXFYKHCQHPMFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468248   

TargetEpidermal growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468248(CHEMBL4290869)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468248(CHEMBL4290869)
Affinity DataIC50: 19nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468248(CHEMBL4290869)
Affinity DataIC50: 33nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed