BDBM50468249 CHEMBL4280817

SMILES Brc1ccc(cc1)C1CC(=NN1C1=NC(=O)CS1)c1ccncc1

InChI Key InChIKey=JWLCIIIANMLPEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468249   

TargetEpidermal growth factor receptor(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468249(CHEMBL4280817)
Affinity DataIC50: 9nMAssay Description:Inhibition of 6x-His-tagged human EGFR cytoplasmic domain (645 to 1186 amino acids) assessed as reduction in autophosphorylation pre-incubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed