BDBM50468415 CHEMBL4282937::US11834432, Compound S1
SMILES CNC(=O)c1cccc2cc(Oc3ccnc(NC(=O)c4ccc(OCCN5CC(F)C5)cc4)c3)ccc12
InChI Key InChIKey=OEUZDCDCIGWRHX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50468415
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
US Patent
Affinity DataIC50: <100nMAssay Description:1. Enzyme reaction substrate μPoly(Glu,Tyr)4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA based spectrophotometric methodMore data for this Ligand-Target Pair