BDBM50468597 CHEMBL4293771

SMILES NC(=O)c1ccc(OCc2cccc(Br)c2)cc1

InChI Key InChIKey=WNYIDDKTEYNPSM-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50468597   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PARP2 (1 to 583 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PARP10 (809 to 1017 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 13 hrs by fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TNKS2 (873 to 1161 residues) (unknown origin) expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50:  630nMAssay Description:Inhibition of PARP14 (unknown origin) using NAD+ as substrate incubated for 18 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed