BDBM50469123 CHEMBL1210878

SMILES COc1cccc(C=C2c3cccc(Cl)c3C(=O)c3c(Cl)cccc32)c1O

InChI Key InChIKey=WDTVZQDDTHDQEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469123   

TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469123BDBM50469123(CHEMBL1210878)
Affinity DataIC50: 730nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469123BDBM50469123(CHEMBL1210878)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469123BDBM50469123(CHEMBL1210878)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469123BDBM50469123(CHEMBL1210878)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed