BDBM50469124 CHEMBL113332

SMILES COc1ccc(C=C2c3ccccc3C(=O)c3ccccc32)c(O)c1

InChI Key InChIKey=RMFPELSCPSUOFY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469124   

TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469124BDBM50469124(CHEMBL113332)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469124BDBM50469124(CHEMBL113332)
Affinity DataIC50: 232nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469124BDBM50469124(CHEMBL113332)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469124BDBM50469124(CHEMBL113332)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed