BDBM50469461 CHEMBL4288210

SMILES [H][C@@]12CN(c3nc(nc(n3)-c3cnc(N)cc3C(F)F)N3C[C@@]4([H])C[C@]3([H])CO4)[C@@]([H])(CO1)C2

InChI Key InChIKey=MQZZAZDYXDOJJI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469461   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469461BDBM50469461(CHEMBL4288210)
Affinity DataKi:  308nMAssay Description:Binding affinity to recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus after 1 hr by TR-FRET displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50469461BDBM50469461(CHEMBL4288210)
Affinity DataKi:  4.63E+3nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged P110alpha catalytic domain (unknown origin) after 1 hr by TR-FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed