BDBM50469464 CHEMBL4293439

SMILES C[C@H]1CN(C[C@@H](C)O1)c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1C[C@H](C)O[C@H](C)C1

InChI Key InChIKey=QPGPHZZWCIESIO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469464   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469464BDBM50469464(CHEMBL4293439)
Affinity DataKi:  650nMAssay Description:Binding affinity to recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus after 1 hr by TR-FRET displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50469464BDBM50469464(CHEMBL4293439)
Affinity DataKi:  1.54E+4nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged P110alpha catalytic domain (unknown origin) after 1 hr by TR-FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed