BDBM50472044 CHEMBL145824

SMILES Cc1oc(nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccc(CO)cc2)C(O)=O)cc1)-c1ccccc1

InChI Key InChIKey=WVGWSUASRKELLX-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50472044   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50472044(CHEMBL145824)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50472044(CHEMBL145824)
Affinity DataEC50:  17nMAssay Description:in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50472044(CHEMBL145824)
Affinity DataEC50:  174nMAssay Description:-log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed