BDBM50473087 CHEMBL341671

SMILES Cc1cc2CCN3c2c(c1)C(=N[C@@H](NC(=O)c1c(Cl)cncc1Cl)C3=O)c1ccccc1

InChI Key InChIKey=YNSCYOBZGPPEEP-QFIPXVFZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50473087   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50473087(CHEMBL341671)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of phosphodiesterase 3 (PDE3) isolated from the dog aortaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50473087(CHEMBL341671)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of phosphodiesterase 1/5 isozyme (PDE1/5) mixture isolated from the guinea pig trachea.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50473087(CHEMBL341671)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed