BDBM50474151 CHEMBL292521

SMILES [H][C@@]12C[C@@H]([C@H](CC)CN1CCc1c2[nH]c2cccc(O)c12)C(=C/OC)\C(=O)OC

InChI Key InChIKey=IIRZCWUQUBSIPF-XZNUVMSOSA-N

Data  7 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50474151   

TargetMu-type opioid receptor(Guinea pig)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  12nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  216nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.88E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  2.95E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  3.09E+4nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  858nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  422nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed