BDBM50474158 CHEMBL61667

SMILES COc1ccc(C2=NN(c3ccc(C4=NNC(=O)CC4C)cc3)C(=O)C3CC=CCC23)cc1Cl

InChI Key InChIKey=IHTDRAFPVZMGCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50474158   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474158BDBM50474158(CHEMBL61667)
Affinity DataIC50: 79nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474158BDBM50474158(CHEMBL61667)
Affinity DataIC50: 100nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed