BDBM50474162 CHEMBL59953

SMILES COc1ccc(C2=NN(CC(=O)Nc3ccc(-c4ccc(O)nn4)cc3)C(=O)C3CC=CCC23)cc1OC

InChI Key InChIKey=OTTVHKKGMZTQQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50474162   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474162BDBM50474162(CHEMBL59953)
Affinity DataIC50: 7.90nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474162BDBM50474162(CHEMBL59953)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed