BDBM50474337 CHEMBL141502

SMILES COc1ccc2[nH]cc(CCNCc3ccc(\C=C\C(=O)NO)cc3)c2c1

InChI Key InChIKey=SKBXAZQJXDJNFI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50474337   

TargetHistone deacetylase 3(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50474337(CHEMBL141502)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50474337(CHEMBL141502)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50474337(CHEMBL141502)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50474337(CHEMBL141502)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50474337(CHEMBL141502)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed