BDBM50474424 CHEMBL153051

SMILES c1nc(C[C@@H]2CCNC2)c[nH]1

InChI Key InChIKey=YGGBVTGACIFVRB-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50474424   

TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474424BDBM50474424(CHEMBL153051)
Affinity DataEC50:  0.389nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474424BDBM50474424(CHEMBL153051)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474424BDBM50474424(CHEMBL153051)
Affinity DataKi:  141nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474424BDBM50474424(CHEMBL153051)
Affinity DataEC50:  1.02E+3nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed