BDBM50475335 CHEMBL2113078

SMILES Oc1ccc2c3c1O[C@H]1c4c(c5c(n4Cc4ccccc4)[C@@H]4Oc6c(O)ccc7c6[C@@]46CCN(CC4CC4)[C@H](C7)[C@]6(O)C5)C[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314

InChI Key InChIKey=YFEFMSMEIWBCRN-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50475335   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475335BDBM50475335(CHEMBL2113078)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [3H]diprenorphine binding to human opioid receptor kappa 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475335BDBM50475335(CHEMBL2113078)
Affinity DataKi:  8.60nMAssay Description:Inhibition of [3H]diprenorphine binding to rat Opioid receptor delta 1 expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475335BDBM50475335(CHEMBL2113078)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]diprenorphine binding to rat Opioid receptor mu 1 expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475335BDBM50475335(CHEMBL2113078)
Affinity DataEC50:  187nMAssay Description:Agonist activity against rat Opioid receptor mu 1 expressed in C6 cells in [35S]-GTP-gamma S binding assay More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475335BDBM50475335(CHEMBL2113078)
Affinity DataEC50:  1.91E+3nMAssay Description:Agonist activity against human Opioid receptor kappa 1 expressed in CHO cells in [35S]-GTP-gamma S binding assay More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed