BDBM50476158 CHEMBL222754

SMILES O=C1CCC(N2Cc3cc(NC(=O)C4CCCCC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=QCGHECSNQIAFRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476158   

TargetCereblon/Casein kinase I alpha(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476158BDBM50476158(CHEMBL6133892)
Affinity DataEC50:  137nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed