BDBM50476388 CHEMBL2113281

SMILES O=Cc1cc2ccc(C(=O)Nc3cccc4c5c([nH]c34)[C@@H]3Oc4c(O)ccc6c4[C@@]34CCN(CC3CC3)[C@H](C6)[C@]4(O)C5)cc2cc1C=O

InChI Key InChIKey=FAAITYPIDMPBCP-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50476388   

TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataIC50: 0.460nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]diprenorphine from delta opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataIC50: 20nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum longitudinal muscleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476388BDBM50476388(CHEMBL2113281)
Affinity DataIC50: 215nMAssay Description:Ratio of IC50 of drug to naltrindole for delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed