BDBM50477374 CHEMBL247675

SMILES C[C@H]1CN(CC2CC2)CCN1C(=O)OCC1CCCC(N1S(=O)(=O)c1ccc(Cl)cc1)c1cc(F)cc(F)c1

InChI Key InChIKey=CKYOUSJBAOMLEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477374   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50477374(CHEMBL247675)
Affinity DataIC50: 110nMAssay Description:Inhibition of gamma-secretase mediated amyloid beta-40 production in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed