BDBM50477388 CHEMBL246863

SMILES CN1CN(C)C2(CCN(CC2)C(=O)OCC2CCCC(N2S(=O)(=O)c2ccc(Cl)cc2)c2cc(F)cc(F)c2)C1=O

InChI Key InChIKey=HZAVUUXVJPCTKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477388   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50477388(CHEMBL246863)
Affinity DataIC50: 27nMAssay Description:Inhibition of gamma-secretase mediated amyloid beta-40 production in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed