BDBM50477391 CHEMBL247264

SMILES Fc1cc(F)cc(c1)[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(Cl)cc1)C1(CC1)OC(=O)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=VOQKFRKBIAKGJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477391   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50477391(CHEMBL247264)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of gamma-secretase mediated amyloid beta-40 production in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed