BDBM50477871 CHEMBL443502

SMILES Oc1ccc2CN(Cc3cccc4ccccc34)C(=O)c2c1O

InChI Key InChIKey=GVNRPHJSVCMRED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50477871   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50477871(CHEMBL443502)
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase L(Andes orthohantavirus)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50477871(CHEMBL443502)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of N-terminal His-tagged ANDV cap-ENDO expressed in Escherichia coli BL21 Gold (DE3) using 6-FAM/BHQ-1-labeled 12mer poly(A) ssRNA as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase L(Toscana virus)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50477871(CHEMBL443502)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of N-terminal His-tagged TOSV cap-ENDO expressed in Escherichia coli BL21 Gold (DE3) using 6-FAM/BHQ-1-labeled 12mer poly(A) ssRNA as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase L(Bunyavirus La Crosse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50477871(CHEMBL443502)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of N-terminal His-tagged LACV cap-ENDO expressed in Escherichia coli BL21 Gold (DE3) using 6-FAM/BHQ-1-labeled 12mer poly(A) ssRNA as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50477871(CHEMBL443502)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed