BDBM50478056 CHEMBL404576

SMILES COc1ccc(CN([C@@H]2CC(F)(F)CCNC2=O)S(=O)(=O)c2ccc(Cl)s2)cn1

InChI Key InChIKey=AVWQTLJCDZCQFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478056   

TargetPresenilin-1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478056(CHEMBL404576)
Affinity DataIC50: 110nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed