BDBM50478377 CHEMBL6078490

SMILES FC(F)c1ccc2ncc(-c3cccc(NC4CCNC4)n3)n2c1

InChI Key InChIKey=IPXVERBAEVXFEM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50478377   

TargetInterleukin-1 receptor-associated kinase 4(Human)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50478377BDBM50478377(CHEMBL6078490)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50478377BDBM50478377(CHEMBL6078490)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50478377BDBM50478377(CHEMBL6078490)
Affinity DataIC50: 15nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed