BDBM50481385 CHEMBL600411

SMILES Cc1cc(C)cc(c1)S(=O)(=O)n1c2nc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=WUEBMTNCIUQAAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50481385   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50481385(CHEMBL600411)
Affinity DataIC50: 20nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase using poly(rA)/pligo(dT) templateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50481385(CHEMBL600411)
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50481385(CHEMBL600411)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50481385(CHEMBL600411)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed