BDBM50481388 CHEMBL603275

SMILES Cc1c(C)c(C)c(S(=O)(=O)n2c(=O)[nH]c3ccc(Cl)cc32)c(C)c1C

InChI Key InChIKey=QTFAFXQTVIFDBF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50481388   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481388BDBM50481388(CHEMBL603275)
Affinity DataIC50: 47nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase using poly(rA)/pligo(dT) templateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481388BDBM50481388(CHEMBL603275)
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481388BDBM50481388(CHEMBL603275)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481388BDBM50481388(CHEMBL603275)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed