BDBM50482016 CHEMBL1091432

SMILES Cn1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ccccc12)C(C)(C)C

InChI Key InChIKey=KSNPWIDVLPHDGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482016   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482016(CHEMBL1091432)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of BRAF V600E mutant ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482016(CHEMBL1091432)
Affinity DataIC50:  11nMAssay Description:Inhibition of human BRAF V600E mutant expressed in baculovirus systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed