BDBM50482176 CHEMBL1085519

SMILES CC[C@@H]1N([C@H](CC)C(=O)c2[nH]ncc12)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=TYZNGDLYLRYJCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482176   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482176(CHEMBL1085519)
Affinity DataIC50: 546nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed