BDBM50482183 CHEMBL1083596

SMILES CC[C@H]1N([C@@H](CC)C(=O)c2[nH]ncc12)S(=O)(=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=KTCZUFKYOCWWRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482183   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482183(CHEMBL1083596)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed