BDBM50482186 6-TERT-BUTYL-4-CYCLOPROPYL-5-(6-(TRIFLUOROMETHYL)PYRIDIN-3-YLSULFONYL)-5,6-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-7(4H)-ONE (STRUCTURAL MIX)

SMILES CC(C)(C)C1N(C(C2CC2)c2cn[nH]c2C1=O)S(=O)(=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=PMTRKYRHVQKGGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482186   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482186(6-TERT-BUTYL-4-CYCLOPROPYL-5-(6-(TRIFLUOROMETHYL)P...)
Affinity DataIC50: 71nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482186(6-TERT-BUTYL-4-CYCLOPROPYL-5-(6-(TRIFLUOROMETHYL)P...)
Affinity DataIC50: 71nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed